We present a 58 years old woman with multiple sclerosis diagnosed in 2007, she was treated with interferon and methylprednisolone with a stable disease until last year. Multiple sclerosis ms is a chronic inflammatory and neurodegenerative disease characterized by focal areas of demyelinationaxonal damage known as plaques. The clinical course is usually characterized by severe. It is the leading cause of disability in this group. Ms in childhood, like in adults, is believed to involve a complex interaction between environmental triggers such as infections, genetic predisposition, and an abnormal autoimmune response. It is a demyelinating disease of the central nervous system whose evolution is unpredictable and its effects and symptoms are varied1,2. Multiple sclerosis ms is the most common inflammatory disease of human central nervous system cns, which is characterized by inflammatory demyelination and neuroaxonal injuryloss. Multiple sclerosis ms is infrequent in childhood 0. Using the methodology of medicine based on the evidence the levels of evidence and the degrees of recommendation were established. Please use one of the following formats to cite this article in your essay, paper or report. There are different etiological hypotheses talking of a close interrelation among predisposing genetic factors and dissimilar environmental factors, able to give raise to autoimmune response. However, the disco v e r y of new ways of diagnosis as the magnetic re sonance imaging mri and the new tre a t m e n t s such as interferon 1a and 1b have provided an im p o r tant change in pronostic and quality of. Recently she had had multiple episodes of exacerbations.
A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. If you continue browsing the site, you agree to the use of cookies on this website. The diagnostic criteria currently used include clinical or paraclinical demonstration of the dissemination of these lesions in space and time, and the exclusion of alternative. Multiple sclerosis ms is a chronic, autoimmune, inflammatory, demyelinating disease of the central nervous system. Multiple sclerosis main anatomopatological observation is the immunological destruction of myelin1. Agencia dinformacio, avaluacio i qualitat en salut. Multiple sclerosis is the major cause of neurological disability in young and middleaged adults. Patient was admitted for a rapidly progressive neurological deterioration.
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